{"id":7265,"date":"2025-05-13T23:35:31","date_gmt":"2025-05-13T21:35:31","guid":{"rendered":"https:\/\/decure.com.pl\/ovarian-tissue-regeneration\/"},"modified":"2025-08-10T23:31:06","modified_gmt":"2025-08-10T21:31:06","slug":"ovarian-tissue-regeneration","status":"publish","type":"page","link":"https:\/\/decure.com.pl\/en\/ovarian-tissue-regeneration\/","title":{"rendered":"Ovarian tissue regeneration"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7265\" class=\"elementor elementor-7265 elementor-6876\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3780541 elementor-section-stretched elementor-section-content-middle elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3780541\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-932caba\" data-id=\"932caba\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-dd5afcf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dd5afcf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-6a22311\" data-id=\"6a22311\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-48c0e19 elementor-widget elementor-widget-image\" data-id=\"48c0e19\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"576\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/Regeneracja-tkanki-jajnika-Rzepka-Kaczynski-archiwum-wlasne-DeCure-1-768x576.png\" class=\"attachment-medium_large size-medium_large wp-image-7166\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/Regeneracja-tkanki-jajnika-Rzepka-Kaczynski-archiwum-wlasne-DeCure-1-768x576.png 768w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/Regeneracja-tkanki-jajnika-Rzepka-Kaczynski-archiwum-wlasne-DeCure-1-300x225.png 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/Regeneracja-tkanki-jajnika-Rzepka-Kaczynski-archiwum-wlasne-DeCure-1-1024x768.png 1024w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/Regeneracja-tkanki-jajnika-Rzepka-Kaczynski-archiwum-wlasne-DeCure-1.png 1386w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-954c97b\" data-id=\"954c97b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-965571b elementor-widget elementor-widget-heading\" data-id=\"965571b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Ovarian tissue regeneration<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2131784 elementor-widget elementor-widget-spacer\" data-id=\"2131784\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-20264c9 elementor-widget elementor-widget-text-editor\" data-id=\"20264c9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Premature ovarian insufficiency (POI) affects 1% to 3.7% of women of reproductive age. This condition is characterized by the occurrence of typical menopausal symptoms below the age of 40, with a simultaneous increase in FSH and undetectable serum AMH levels. Considering that menopause in the Caucasian population occurs on average at 51.4 years, this is a significant shortening of the biological function of ovaries as endocrine glands in humans. Currently, there are two main theories explaining the etiology of the disease: genetic factors responsible for premature depletion of ovarian reserve, with an associated increased risk of cancer and shortened lifespan; autoimmune diseases &#8211; when antibodies against endocrine glands penetrate the follicular fluid and damage oocytes. The treatment for patients with POI is hormone replacement therapy. For patients who want to become mothers, oocyte donation is the treatment of choice.     <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2dc6623 elementor-section-stretched elementor-section-content-middle elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2dc6623\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e3f7de3\" data-id=\"e3f7de3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2d0465c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2d0465c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-bb68a4e\" data-id=\"bb68a4e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68b2d4c elementor-widget elementor-widget-text-editor\" data-id=\"68b2d4c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Mesenchymal stem cells are multipotent cells that have the ability to differentiate and mature into cartilage, bone, and fat cells, and can help and interact with other stem cells. They also have the ability to modulate certain elements of the immune system. Mesenchymal stem cells are characterized by the ability to self-renew and differentiate into cartilage, bone, and fat, to adhere and grow in vitro. Mesenchymal stem cells can have different origins. Embryonic mesenchymal stem cells, fetal stem cells &#8211; from the umbilical cord and Wharton&#8217;s jelly, and adult mesenchymal cells from bone marrow and adipose tissue can be distinguished.    <\/p><p>Mesenchymal stem cells derived from Wharton&#8217;s jelly meet the criteria described above: they are self-renewing and can differentiate into various tissues, not only bones, cartilage, and fat, but also into:<\/p><ul><li>striated muscle cells,<\/li><li>cardiomyocytes,<\/li><li>hepatocytes,<\/li><li>pancreatic Langerhans cells,<\/li><li>nerve cells.<\/li><\/ul><p>They can also participate in the regeneration of retinal structures. On their surface, they have type I tissue compatibility antigens (HLA &#8211; I), but do not have surface markers of type II HLA antigens. The above immunological properties of these cells result in both a lack of immune response to mesenchymal cell transplantation from another donor and a lack of recognition by allogeneic mesenchymal cells of the recipient as foreign structures. It is believed that mesenchymal stem cells act as a local coordinator of tissue repair. Repair of damaged tissue occurs through the regulation of endogenous regenerative processes, rather than through the replacement of damaged tissue with de novo structures.    <\/p><p>Fetal MSCs have a greater expansion potential in in vitro culture than adult mesenchymal stem cells. Many authors believe that this is a consequence of two passages of primary hematopoietic cells from the embryo to placental structures and back. First, between 4 and 12 days of embryogenesis, hematopoietic cells migrate from the yolk sac to the placenta through the primitive umbilical cord. Then, during the second migration, MSCs are transferred in the opposite direction. They return from the placenta back to the fetus: to the liver, and then to the bone marrow. Scientists have hypothesized that during this migration, mesenchymal cells in Wharton&#8217;s jelly become &#8220;trapped&#8221; from early embryogenesis, throughout pregnancy, until birth.     <\/p><p>Recent discoveries made in the field of stem cell origin and development prove that primordial germ cells (PGCs) and their deposits, remaining in the developing tissues of the organism &#8211; very small embryonic-like stem cells (VSEL) &#8211; play a key role in the regeneration process. Some earlier studies suggest that primordial stem cells (very small MSCs deposited in the ovarian tract) undergo asymmetric cell divisions and are able to produce oogonial\/germinal stem cells, which ultimately become oocytes. The factor stimulating vsMSCs to divide may be mesenchymal stem cells and the exosomes they produce. Animal models have shown that stimulation of primordial stem cells to produce oocytes is able to restore the hormonal and procreative function of ovaries previously damaged by radio- and chemotherapy. This suggests that similar benefits should be experienced by women who have developed POI.    <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4efeb318 elementor-section-content-middle elementor-reverse-tablet elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4efeb318\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2a5333e\" data-id=\"2a5333e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7847113c elementor-widget elementor-widget-heading\" data-id=\"7847113c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">DeCure<br>Own experiences<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-842e86e elementor-widget elementor-widget-spacer\" data-id=\"842e86e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e90ccd3 elementor-widget elementor-widget-text-editor\" data-id=\"e90ccd3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>We have been conducting research using mesenchymal stem cells (MSC) in patients with premature ovarian insufficiency (POI) since 2016.<\/p><p>We have experience with using stem cells obtained from Wharton&#8217;s jelly, adipose tissue, and bone marrow.<\/p><p>We administer the biological material directly into the ovarian tissue during laparoscopy.<\/p><p>The use of MSCs from the umbilical cord allowed for the restoration of hormonal and procreative function in the ovarian tissue. We observe the biological effect measured as the concentration of sex hormones in the blood serum in patients after administration of biological material after a period of 3 to 6 months. The graph shows the results of a 35-year-old patient with premature menopause (FSH 146 U\/l, LH 83 U\/l, E2 17 pg\/ml). After the administration of stem cells, there was a return to normal sex hormone values (FSH 2.5 U\/l, E2 149 pg\/ml)   <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-fb0306b\" data-id=\"fb0306b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ec615d9 elementor-widget elementor-widget-image\" data-id=\"ec615d9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-1-1-1-300x300.png\" class=\"attachment-medium size-medium wp-image-7168\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-1-1-1-300x300.png 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-1-1-1-150x150.png 150w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-1-1-1.png 600w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fe32dc6 elementor-widget elementor-widget-image\" data-id=\"fe32dc6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"219\" height=\"219\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-2-1-1.png\" class=\"attachment-medium size-medium wp-image-7169\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-2-1-1.png 219w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-2-1-1-150x150.png 150w\" sizes=\"(max-width: 219px) 100vw, 219px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7baac17 elementor-section-stretched elementor-section-content-middle elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7baac17\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-834502a\" data-id=\"834502a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-26e93fb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"26e93fb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-a086c20\" data-id=\"a086c20\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2582a4a elementor-widget elementor-widget-image\" data-id=\"2582a4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-1024x683.png\" class=\"attachment-large size-large wp-image-7170\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-1024x683.png 1024w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-300x200.png 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-768x512.png 768w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-1536x1024.png 1536w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-regeneracja-jajnika-stats-1-2048x1366.png 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1308ccb elementor-section-content-middle elementor-reverse-tablet elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1308ccb\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0abf308\" data-id=\"0abf308\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c3c4150 elementor-widget elementor-widget-text-editor\" data-id=\"c3c4150\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><strong>Changes are also observed during transvaginal ultrasound examination.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-58e0458 elementor-section-content-middle elementor-reverse-tablet elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"58e0458\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e3bd24e\" data-id=\"e3bd24e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ebf33fb elementor-widget elementor-widget-image\" data-id=\"ebf33fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-1.jpg\" class=\"attachment-large size-large wp-image-7172\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-1.jpg 800w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-1-300x225.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-1-768x576.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7966519\" data-id=\"7966519\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-302c5a7 elementor-widget elementor-widget-image\" data-id=\"302c5a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-2.jpg\" class=\"attachment-large size-large wp-image-7171\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-2.jpg 800w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-2-300x225.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-2-768x576.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-781c76c elementor-section-content-middle elementor-reverse-tablet elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"781c76c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-443f4f3\" data-id=\"443f4f3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d5853fb elementor-widget elementor-widget-text-editor\" data-id=\"d5853fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">TV ultrasound image of the uterus with endometrium and ovary <strong>before MSC administration.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a25daa elementor-widget elementor-widget-image\" data-id=\"6a25daa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-3.jpg\" class=\"attachment-large size-large wp-image-7174\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-3.jpg 800w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-3-300x225.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-3-768x576.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2172ec1\" data-id=\"2172ec1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5e68f2a elementor-widget elementor-widget-text-editor\" data-id=\"5e68f2a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">TV ultrasound image of the uterus with endometrium and ovary <strong>after MSC administration.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c311591 elementor-widget elementor-widget-image\" data-id=\"c311591\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-4.jpg\" class=\"attachment-large size-large wp-image-7173\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-4.jpg 800w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-4-300x225.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-4-768x576.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b409fc7 elementor-section-content-top elementor-reverse-tablet elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b409fc7\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-b151354\" data-id=\"b151354\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-17e9002 elementor-widget elementor-widget-text-editor\" data-id=\"17e9002\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">Patients have a chance to achieve pregnancy<br>both in the IVF program<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fe775cb elementor-widget elementor-widget-image\" data-id=\"fe775cb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-5-300x300.jpg\" class=\"attachment-medium size-medium wp-image-7178\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-5-300x300.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-5-150x150.jpg 150w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-5.jpg 404w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f32e0d3 elementor-widget elementor-widget-image\" data-id=\"f32e0d3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-6-300x300.jpg\" class=\"attachment-medium size-medium wp-image-7177\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-6-300x300.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-6-150x150.jpg 150w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-6.jpg 338w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-94960cc elementor-widget elementor-widget-text-editor\" data-id=\"94960cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><em>Blastocyst \u2013 embryo on day 5 of life<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-11812bf\" data-id=\"11812bf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5f26336 elementor-widget elementor-widget-text-editor\" data-id=\"5f26336\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">and as a result of<br>spontaneous conception,<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0eccfc8 elementor-widget elementor-widget-image\" data-id=\"0eccfc8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"260\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-7-300x260.jpg\" class=\"attachment-medium size-medium wp-image-7176\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-7-300x260.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-7.jpg 553w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01c9724 elementor-widget elementor-widget-image\" data-id=\"01c9724\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"260\" src=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-8-300x260.jpg\" class=\"attachment-medium size-medium wp-image-7175\" alt=\"\" srcset=\"https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-8-300x260.jpg 300w, https:\/\/decure.com.pl\/wp-content\/uploads\/2025\/05\/decure-usg-8.jpg 553w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-23df4c0 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"23df4c0\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5abbc1d\" data-id=\"5abbc1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f0b0871 elementor-widget elementor-widget-template\" data-id=\"f0b0871\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"section\" data-elementor-id=\"7246\" class=\"elementor elementor-7246 elementor-5105 elementor-5105\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-31282915 elementor-section-height-min-height elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"31282915\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-118d2e87\" data-id=\"118d2e87\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c943d5b elementor-widget elementor-widget-heading\" data-id=\"c943d5b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Contact us today for more information and to schedule a consultation!<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-722fd6c7 elementor-widget elementor-widget-spacer\" data-id=\"722fd6c7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-63442914 content-align-mobile-center icon-position-mobile-top icon-vertical-align-center icon-vertical-align-mobile-center elementor-widget__width-auto elementor-widget-mobile__width-inherit content-align-left icon-box-vertical-align-top icon-position-left elementor-widget elementor-widget-the7_icon_box_widget\" data-id=\"63442914\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"the7_icon_box_widget.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"the7-box-wrapper the7-elementor-widget the7_icon_box_widget-63442914\">\t\t\t<div class=\"box-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<a class=\"elementor-icon-div\" href=\"tel:+48604514450\">\t\t\t\t\t\t<div class=\"elementor-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"feather feather-phone-call\"><\/i>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\t\t\t\t\t\t\t\t<div class=\"box-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"box-heading\">\n\t\t\t\t\t\t\t<a href=\"tel:+48604514450\">\t\t\t\t\t\t\t\t  +48 604 514 450\t\t\t\t\t\t\t<\/a>\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-394273f0 elementor-widget__width-initial elementor-align-justify elementor-widget elementor-widget-the7_button_widget\" data-id=\"394273f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"the7_button_widget.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\"><a href=\"https:\/\/decure.com.pl\/en\/contact\/\" class=\"box-button elementor-button elementor-size-lg\">Contact<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Ovarian tissue regeneration Premature ovarian insufficiency (POI) affects 1% to 3.7% of women of reproductive age. This condition is characterized by the occurrence of typical menopausal symptoms below the age of 40, with a simultaneous increase in FSH and undetectable serum AMH levels. Considering that menopause in the Caucasian population occurs on average at 51.4&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":20,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7265","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ovarian tissue regeneration - DeCure Medical Research<\/title>\n<meta name=\"description\" content=\"Breakthrough therapies using mesenchymal stem cells that help regenerate ovarian tissue and restore function\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/decure.com.pl\/en\/ovarian-tissue-regeneration\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ovarian tissue regeneration - 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